Cisplatin and hyponatremia

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August undefined, 2024

WebSep 1, 2002 · (6) The mechanism of cisplatin-induced hyponatremia is thought to be mainly renal salt wasting syndrome (RSWS), (7) (8) (9) (10) (11) (12) (13) and sometimes the syndrome of inappropriate... WebA 66-year-old woman with small-cell lung cancer was administered chemo-radiotherapy consisting of cisplatin (CDDP) and etoposide (ETP). From day 3, she developed vomiting and hyponatremia that persisted despite fluid infusion and cortico-steroid administration.

Cisplatin nephrotoxicity - UpToDate

WebThe incidence of hyponatremia secondary to cisplatin can be as high as 43%, [ 6] the mechanism of action by which cisplatin induces hyponatremia is controversial. There … WebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … fix corrupted windows 11 files

Overview of the treatment of hyponatremia in adults - UpToDate

WebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, … WebJun 11, 2024 · INTRODUCTION Hyponatremia represents a relative excess of water in relation to sodium. It can be induced by a marked increase in water intake (primary polydipsia) and/or by impaired water excretion due, for example, to advanced kidney failure or persistent release of antidiuretic hormone (ADH). (See "Causes of hypotonic … WebJan 27, 2024 · Urothelial cancer of the bladder, renal pelvis, ureter, and other urinary organs is the fifth most common cancer in the United States, and systemic platinum-based chemotherapy remains the standard of care for first-line treatment of advanced/metastatic urothelial carcinoma (UC). Until recently, there were very limited options for patients who … can lsil be false positive

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WebMar 24, 2024 · Carboplatin and oxaliplatin may have a lower incidence of hyponatremia relative to cisplatin containing regimens. 10 Of course, malignancy-specific risks of … WebFeb 16, 2024 · were treated with cisplatin for various cancers, 8.9% and 1.7% developed grade 3 (serum sodium 120–129mEq/L) and grade 4 ( fix corrupted word fileWebHyponatremia is one of the common electrolyte disorders associated with cisplatin (CDDP) administration. We report here two cases of hyponatremia associated with CDDP. Case 1 : A 75-year-old man with urothelial carcinoma of bladder (cT3N1M0) underwent neoadjuvant chemotherapy with CDDP and gemcitabi … can ls fit in a 1986 supra

"WebDec 16, 2024 · Cisplatin (CDDP; cis-dichlorodiammine platinum [II]) is a non-specific drug of the cell cycle with strong cytotoxicity and broad-spectrum antitumor effects; it is widely used in urogenital system tumors, malignant lymphoma, breast cancer, head and neck cancer, non-small cell lung cancer, etc. ( 1 – 3) Cisplatin-induced nephrotoxicity is … " - Cisplatin and hyponatremia

Cisplatin and hyponatremia

Gemcitabine and cisplatin (GC) - Cancer Research UK

WebAug 21, 2014 · The differential diagnosis between RSWS and SIADH for hyponatremic patients is sometimes difficult because of similarities in their clinical features, but careful consideration is needed to make... WebMay 17, 2024 · If you have moderate, chronic hyponatremia due to your diet, diuretics or drinking too much water, your doctor may recommend temporarily cutting back on fluids. …

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WebNational Center for Biotechnology Information WebSep 15, 2024 · Serum Electrolyte Disturbances - Hypomagnesemia, hypocalcemia, hyponatremia , hypokalemia, and hypophosphatemia have been reported to occur in patients treated with cisplatin (cisplatin injection) and are probably related to renal tubular damage. Tetany has occasionally been reported in those patients with hypocalcemia and …

WebSep 1, 2024 · Cisplatin for injection can cause severe hypersensitivity reactions, including anaphylaxis and death. Manifestations have included facial edema, wheezing, tachycardia, and hypotension. Hypersensitivity reactions have occurred within minutes of administration to patients with prior exposure toCisplatin for injection. WebHyponatremia is a common potential complication in cancer patients. It can be related to anticancer medical therapy. Vincristine, vinblastine, cisplatin and cyclophosphamide are the chemotherapeutic agents most frequently associated with hyponatremia. More recently, analogs such as carboplatin and ifosfamide have also been incriminated.

WebOnset of severe hyponatremia following cisplatin (CDDP) administration has been previously reported. However, the risk factors associated with hyponatremia still remain … WebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, diabetes, and serum albumin < 3.5g/L. The association between C-AKI and hypokalemia, hypomagnesemia or hyponatremia has not been well characterized to date.

WebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis showed that the use of generic CDDP increased the incidence of hyponatremia (odds ratio =5.661, 95% confidence interval =1.403–22.839; P =0.015). Conclusion: Oncologists … fix corrupted word documentWebApr 12, 2024 · AKI-related cisplatin may also be associated with tubulopathies, such as Fanconi-like syndrome, hypomagnesemia, salt-loosing syndrome and distal renal tubular acidosis . Tubular dysfunction is characterized by electrolyte disorders such as hyponatremia, hypokalemia and hypomagnesemia. can lsd help schizophreniaWebMar 23, 2024 · With a median follow-up of 12 months, 25 patients in the first-line group and 15 patients in the second-line group died of UTUC. For cisplatin-ineligible first-line patients, the median OS was 18.0 months (95% CI 4.1–31.9), the 1-year OS rate was 65.4%, and the median PFS was 5.0 months (95% CI 2.0–8.0; Figure 1A,B). can lsl be taken at half pay in nswWebcisplatin, docetaxel and 5-fluorouracil-containing chemotherapy who suffered from acute-onset consciousness disturbance due to hyponatremia just after administration of … can ls speak koreanWebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are … fix corrupt exe file flash drive usb driveWebJul 22, 2024 · Cisplatin-induced kidney toxicity is reviewed here. The use of cisplatin in patients with pre-existing kidney dysfunction and the kidney effects of the platinum … can lse students use ucl libraryWebMay 17, 2024 · Hyponatremia occurs when the concentration of sodium in your blood is abnormally low. Sodium is an electrolyte, and it helps regulate the amount of water that's … canl stock price today