Hif-1 alpha protein
Web30 de jan. de 2003 · HIF-1 alpha stability regulation initiates a complex biological response that allows cells to act appropriately to meet patho-physiological situations of decreased … WebNuclear HIF-1 engages p300/CBP for binding to hypoxic response elements (HREs). This process induces transcription and regulation of genes including EPO, VEGF, iNOS2, ANGPT1 and OCT4 (4,5). Under normoxic conditions, the HIF-1 alpha subunit is rapidly targeted and degraded by the ubiquitin proteasome system.
Hif-1 alpha protein
Did you know?
Web1 mg/mL: Formule: PBS with 0.05% sodium azide: Numéro d’ordre du gène: Q16665, Q61221, O35800: Symboles de gène(s) HIF1A: Immunogène: A fusion protein including residues 530-825 of the mouse HIF-1 alpha protein. Quantité: 100 μL: Primaire ou secondaire: Primary: Espèces cibles: Rat, Rabbit, Non-human Primate, Mouse, Human ... WebFigure 1 Up-regulation of ASAP3 is associated with lung adenocarcinoma. (A) Levels of ASAP3 mRNA in human lung adenocarcinoma tissues and matched adjacent non-neoplastic tissues.(B and C) Western blot analysis of ASAP3 protein levels in three pairs of human lung adenocarcinoma tissues and matched adjacent non-tumorous tissues.ASAP3 …
WebUnder hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate … Induces stabilization of the protein. 1 publication. Sequence: S → A: … We'd like to inform you that we have updated our Privacy Notice to comply … UniRef - UniProt History - UniProt External Links - UniProt Gostaríamos de exibir a descriçãoaqui, mas o site que você está não nos permite. Induces stabilization of the protein. 1 publication. Sequence: S → A: … YTH domain-containing protein 1 · Gene: YTHDC1 (KIAA1966, YT521) · Homo … Web29 de fev. de 2004 · Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian …
Web21 de mar. de 2024 · The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, … WebSummary of HIF1A (bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8) expression in human tissue. Mainly nuclear expression with cases of cytoplasmic expression. ... Hypoxia …
WebThis antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, …
WebProtein target information for Hypoxia-inducible factor 1-alpha (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. city college international students numberWebHIF1A, hypoxia inducible factor 1 subunit alpha Synonyms bHLHe78, HIF1, HIF-1A, HIF-1alpha, HIF-1-alpha, HIF1-ALPHA, MOP1, PASD8 dictionary corner starWebアズワンの【AXEL】84-1432-35 HIF1A (Hypoxia-inducible Factor 1-alpha, HIF-1-alpha, HIF1-alpha, ARNT-interacting Protein, Basic-helix-loop-helix-PAS Protein MOP1, Class … dictionary cpWeb3 de abr. de 2024 · This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta … city college it departmentWebDescription. HIF1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 298 amino acids (530-826) and having a molecular mass of … dictionary courseworkWebHIF1-alpha (HIF1A) is a subunit of HIF1, which is a transcription factor found in mammalian cells cultured under reduced oxygen tension. HIF-1 is a heterodimer consisting of an alpha and beta subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors. dictionary coterieWebThe mTOR and HIF-1 alpha protein decreased about five folds while the VEGF decreased about three folds compared with control and NC groups (P<0.05). Figure 2 Vandetanib … dictionary covered