Phospho s727

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August undefined, 2024

WebHigh expression of histone deacetylase 2 (HDAC2) is recognized as a marker of invasive breast cancer (BC). HDAC2 is not only responsible for enhancing tumor cell growth, development, and anti-apoptosis, but also plays a significant role in regulating PD-L1 on the surface of tumor cells.

Regulation of Stat3 transcriptional activity by the ... - ScienceDirect

WebA phospho specific peptide corresponding to residues surrounding Serine 727 of human Stat-1 was used as an immunogen. This antibody only … WebHuman/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA RayBiotech The store will not work correctly in the case when cookies are disabled. JavaScript seems to be disabled in … smallest possible nether portal

Human Phospho-STAT3 (S727) Antibody AF4934: R&D Systems

WebUsing a combination of HepG2-stat3-knockdown cells reconstituted with various STAT3 mutants and protein kinase inhibitors, we showed that phospho-S727 has an intrinsic … WebPhospho-STAT1 (Ser727) Antibody (PA5-97355) in ICC/IF Immunofluorescence analysis of Signal transducer and activator of transcription 1-alpha/beta was performed using 70% confluent log phase HeLa cells treated with IFN gamma (100 ng/mL for 30 minutes). WebDec 1, 2024 · Besides, phospho-TBK1 S511 was not induced by AKT1 but augmented upon the suppression of AKT activity, ... Rabbit monoclonal anti- STAT1 (phospho S727) Cell Signaling Technology: Cat#8826; RRID: AB_2773718: Mouse monoclonal anti-Myc Tag: Cell Signaling Technology: Cat#3739, RRID: AB_10889248: smallest positive missing number in an array

On-target JAK2/STAT3 inhibition slows disease progression in …

STAT3 phosphorylation at tyrosine 705 and serine 727 ... - PubMed

WebSep 30, 2008 · S727 phosphorylation enhances the transcriptional activities of Stat3, whereas mutations of S727 compromise Stat3 transactivational activity and downstream effects ( 8 ). Cooperation of both tyrosine and serine phosphorylation is necessary for full activation of Stat3 ( 4 ). WebHere, we studied the role of STAT3 activation on tyrosine 705 (Y705) and serine 727 (S727) in glioma radioresistance. This study explored STAT3 phosphorylation on Y705 (pSTAT3-Y705) and S727 (pSTAT3-S727) in glioma cell lines and in clinical samples. Radiosensitizing effect of STAT3 activation down-modulation by Gö6976 was explored. smallest possible data type alteryxWebPhospho S727 (2) Phospho S51 (1) Asymmetric DiMethyl R3 (1) MonoMethyl R26 (1) Phospho S380 (1) Symmetric DiMethyl R2 (1) Phospho S33 (1) Acetyl K23 (1) Asymmetric DiMethyl R8 (1) DiMethyl K14 (1) MonoMethyl R17 (1) MonoMethyl R8 (1) MonoMethyl R3 (1) Phospho S455 (1) Phospho Thr4 (1) Phospho S259 (1) Phospho S957 (1) Phospho … song of bigizi gentil

"WebApr 23, 2002 · Phosphorylation of S727 in Stat1 can be induced by a variety of stimuli such as IFN-γ, lipopolysaccharide, and UV, and p38 mitogen-activated protein (MAP) kinase has been implicated in lipopolysaccharide- or UV-induced phosphorylation of S727 in Stat1 ( … " - Phospho s727

Phospho s727

Phospho-STAT3(S727) Rabbit mAb - SAB Signalway Antibody

WebHuman Phospho-STAT3 (S727) Antibody Summary Species Reactivity Human Specificity Detects human STAT3 when phosphorylated at S727 in Western blots. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human STAT3 S727 site Accession # P40763 Formulation WebProduct Name Phospho-STAT3(S727) Rabbit mAb; Host Species Rabbit ; Clonality Monoclonal ; Clone No. SY24-09 Purification ProA affinity purified; Applications WB, ICC/IF, IHC, IP; Species Reactivity Hu, RtMs; Immunogen Description Synthetic phospho-peptide corresponding to residues surrounding Ser727 of human STAT3.; Alternative Names …

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WebHuman Phospho-HSP27 (S78/S82) Antibody Summary. Species Reactivity. Human. Specificity. Detects human HSP27 when dually phosphorylated at S78/S82 in Western … WebProperties. Description. Rabbit Monoclonal Antibody to STAT3 (phospho S727) Background. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene.

WebJan 15, 2001 · S727 phosphorylation of STAT1 in interferon-γ (IFN-γ)-treated mouse fibroblasts occurred without a need for p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinases 1 and 2 or c-Jun kinases, and required both an intact SH2 domain and phosphorylation of Y701. WebStat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor comp

WebThis protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. WebProduct Name Phospho-STAT3(S727) Rabbit mAb; Host Species Rabbit ; Clonality Monoclonal ; Clone No. SY24-09; Purification ProA affinity purified; Applications WB, …

WebCitations: (293) The Phospho-Stat3 (Ser727) Antibody from Cell Signaling Technology is a Rabbit Polyclonal antibody to STAT3. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-Stat3 (Ser727) Antibody has been validated for the following applications: Precipitation, ChIP, Immunoprecipitation, and Western Blot.

WebBoster Bio Anti-STAT3 (Phospho-S727) Antibody catalog # A00007S727-2. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100ul in Liquid form antibody. smallest possible bathroomWebJan 11, 2012 · It has been shown that Ser727 of STAT3 is phosphorylated by various kinases, including mitogen-activated kinases (MAPK), H7-sensitive kinase, protein kinase Cδ, cyclin-dependent kinase 5 (CDK5), the mammalian target of rapamycin kinase (mTOR), nemo-like kinase (NLK), death-associated protein kinase 3 (DAPK3), and mitogen- and … smallest possible nuclear weaponWebMay 25, 2000 · The critical importance of S727 phosphorylation for the biological impact of IFN-γ is further supported by studies with mediators of inflammation (LPS, TNF-α), which cooperate with IFN-γ in the... song of bernadette on youtubeWebNov 13, 2024 · Phospho-S727 Stat3 localizes in mitochondria. Recently, Larner and Levy groups described that phospho-Stat3 S727, but not phospho-Stat3 Y705, led to the … smallest portable propane heaterWebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-STAT3 (phospho S727) antibody [E121-31] (ab32143) Research with … song of bernadette wikipediaWebS727 phosphorylation is regulated directly by fibroblast growth factor/Erk signaling and crucial in the transition of mESCs from pluripotency to neuronal commitment. Loss of S727 phosphorylation resulted in significantly reduced neuronal differentiation potential, which could be recovered by a S727 phosphorylation mimic. ... song of bible booksWebWestern blot - Phospho-STAT3-S727 Rabbit pAb (AP0474) Western blot analysis of extracts of various cell lines, using Phospho-STAT3-S727 antibody (AP0474) at 1:1000 dilution.HepG2 cells and C6 cells were treated by PMA/TPA (200 nM) at 37℃ for 30 minutes after serum-starvation overnight.HepG2 cells were treated by CIP (20uL/400ul) at 37℃ for ... song of bhupendra